Near-infrared manipulation of multiple neuronal populations via trichromatic upconversion

oleh: Xuan Liu, Heming Chen, Yiting Wang, Yueguang Si, Hongxin Zhang, Xiaomin Li, Zhengcheng Zhang, Biao Yan, Su Jiang, Fei Wang, Shijun Weng, Wendong Xu, Dongyuan Zhao, Jiayi Zhang, Fan Zhang

Format: Article
Diterbitkan: Nature Portfolio 2021-09-01

Deskripsi

Conventional upconversion nanoparticles (UCNPs) cannot activate multiple neuron populations independently using optogenetics. Here the authors report trichromatic UCNPs with excitation-specific luminescence to allow activation of three distinct neuronal populations in the brain of awake mice.