Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension
oleh: Gi Fay Mok, Leighton Folkes, Shannon A. Weldon, Eirini Maniou, Victor Martinez-Heredia, Alice M. Godden, Ruth M. Williams, Tatjana Sauka-Spengler, Grant N. Wheeler, Simon Moxon, Andrea E. Münsterberg
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-02-01 |
Deskripsi
How paraxial mesoderm formation and differentiation is regulated is unclear. Here, the authors identify accessible chromatin and gene expression signatures that define different stages of paraxial mesoderm development in the chick and identify CREs important for vertebrate anterior–posterior axis formation.