Research progress on the roles of angiopoietin-like protein 8 in the pathogenesis of cardiovascular diseases
oleh: HAN Lijie, HU Chaowei, YU Huahui, QIN Yanwen
| Format: | Article |
|---|---|
| Diterbitkan: | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2024-04-01 |
Deskripsi
Angiopoietin-like protein 8(ANGPTL8) secreted by liver and adipose tissue, is a glycoprotein exerting paramount effects on facilitation of vascular remodeling and regulation of inflammatory response; ANGPTL8 is involved in the initiation and progression of cardiovascular diseases including coronary artery disease, hypertension, aortic aneurysm and pathological cardiac hypertrophy, and holds promise for being a new target for the prevention and treatment of cardiovascular diseases.