A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
oleh: Elva Bonifácio Andrade, Ana Magalhães, Ana Puga, Madalena Costa, Joana Bravo, Camila Cabral Portugal, Adília Ribeiro, Margarida Correia-Neves, Augusto Faustino, Arnaud Firon, Patrick Trieu-Cuot, Teresa Summavielle, Paula Ferreira
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-08-01 |
Deskripsi
Animal models of group-B streptococcal infections are needed to develop effective therapies. Here, Andrade et al. present a mouse model in which the bacteria are transmitted from vaginally colonised pregnant females to their offspring, causing neonatal meningitis and neurological developmental disabilities.