Microwave-Assisted Synthesis of Aryl Phosphonates and Tertiary Phosphine Oxides by the Hirao Reaction
oleh: Bianka Huszár, Zoltán Mucsi, György Keglevich
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2021-11-01 |
Deskripsi
Our group described a green, “P-ligand-free”, Pd(OAc)<sub>2</sub>- or NiCl<sub>2</sub>-catalyzed synthesis under MW conditions. The reactivity of a few aryl derivatives in the Pd(OAc)<sub>2</sub>-catalyzed, “P-ligand-free” P–C coupling reactions under MW condition was also studied. An induction period was observed. Finally, the less known copper(I)-promoted reactions were investigated experimentally. The mechanism was explored by quantum chemical calculations.