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Neuroleptic malign-like syndrome is an emergency condition caused by the withdrawal or dose reduction of anti-Parkinsonian drugs. Quick treatment and correct diagnosis is important for saving life. Basic clinical findings are rigidity, autonomic dysfunction, fever, elevated serum creatinine kinase levels, and confusion. In this study, we present our approach to diagnosis and treatment of a patient with neuroleptic malign-like syndrome in our intensive care unit.