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In patients with Obstructive sleep apnea syndrome (OSAS), preoperative evaluation should be routinely done in all patients with OSAS undergoing surgery or in all patients suspected to have OSAS to avoid problems during perioperative (pre-intra-post) stages. The detection of OSAS severity, the prediction of perioperative anesthesia risk, preoperative medication and difficult entubation should be taken in account. Preventive measures should be taken.