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Objective: The objective of this study is to investigate association between BMI and sleep quality with severity of acne. Methods: A cross-sectional survey conducted using pre-tested questionnaire at Dermatology Department, Mayo Hospital, Lahore from January 2019 to March 2019. A total of 98 participants between the ages of 12-45 years were enrolled after ethical approval. Grades of acne were determined by a consultant dermatologist into 1, 2, 3 and 4 according to severity of the disease. Pittsburgh sleep quality index PSQI is used to assess sleep quality. BMI was also calculated. SPSS-22 was used to analyze data. Results: From 98 patients enrolled in the study, 27 patients (27.6%) were male, 71 patients (72.4%) were female. The highest frequency among severity of acne groups seen in grade 3 was 36 (36.7%) .On average, 25 patients (25.5%) were in grade 1 acne group, 25 patients (25.5%) were in grade 2 Continuous....