Clinical Application of Thromboelastography in Patients With Severe Fever With Thrombocytopenia Syndrome

oleh: Yingbo Li BS, Changjuan An MS, Peng Xue BS, Lina Ni MS, Xia Yu BS, Jiangli Qu BS, Yingjie Yao BS, Chengyong Yu BS

Format: Article
Diterbitkan: SAGE Publishing 2023-06-01

Deskripsi

Aim To investigate the clinical application of thromboelastography (TEG) in severe fever with thrombocytopenia syndrome (SFTS). Methods One hundred and fifty-seven patients with SFTS were included in the study. The participants were distributed into 3 groups; A, B, and C. And 103 patients in group A met the clinical criteria as they exhibited slight liver and kidney dysfunction. Group B consisted of 54 patients with SFTS who were critically ill while group C was a healthy control group with 58 participants. Results Patients with SFTS exhibited lower coagulation than the healthy participants. Group B patients exhibited significantly lower coagulation compared to group A. There was no significant difference in platelet count and fibrinogen content between patients in group A and group B, but platelet aggregation function and fibrinogen activity were significantly lower in group B patients. Conclusion Our results suggest that it is risky to solely rely on platelet count and the fibrinogen in SFTS. Monitoring of TEG and other coagulation indexes should be emphasized.