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Recovering genotypes and phenotypes using allele-specific genes
oleh: Gamze Gürsoy, Nancy Lu, Sarah Wagner, Mark Gerstein
| Format: | Article |
|---|---|
| Diterbitkan: | BMC 2021-09-01 |
Deskripsi
Abstract With the recent increase in RNA sequencing efforts using large cohorts of individuals, surveying allele-specific gene expression is becoming increasingly frequent. Here, we report that, despite not containing explicit variant information, a list of genes known to be allele-specific in an individual is enough to recover key variants and link the individuals back to their genotypes and phenotypes. This creates a privacy conundrum.