A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy
oleh: Guocan Yu, Shan Yu, Manik Lal Saha, Jiong Zhou, Timothy R. Cook, Bryant C. Yung, Jin Chen, Zhengwei Mao, Fuwu Zhang, Zijian Zhou, Yijing Liu, Li Shao, Sheng Wang, Changyou Gao, Feihe Huang, Peter J. Stang, Xiaoyuan Chen
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-10-01 |
Deskripsi
It is challenging to design photosensitizers (PS) with high quantum yields generating singlet oxygen due to severe aggregation between the hydrophobic PSs. Here they develop organoplatinum(II) metallatocage-based PS to overcome these challenges and show excellent antitumor effect.