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A 41-year-old female with retractable epigastric pain due to an invasive neuroendocrine tumor of the pancreas was treated with blockage and radiofrequency ablation of the celiac and splanchnic plexuses. Then, the patient developed back pain, and a bone scan revealed abnormal uptake in the lower thoracic vertebrae despite a normal CT scan. The findings were interpreted as a local invasion of the tumor or iatrogenic post-manipulation inflammation or infection. MRI data presented the destruction of the thoracic 11th and 12th vertebrae, and pathology examination of the open biopsy sample favored inflammatory changes.