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Continuous data breaches targeting the invaluable medical records have become a nemesis for the healthcare organizations. A secure and effective information security model in healthcare web applications can gain and enhance the respect as well as revenue of the healthcare organizations. For achieving this goal, a multi-criteria decision methodology can be a milestone. The authors have used a hybrid integrated Fuzzy Analytical Hierarchy Process-Technique for Order of Preference by Similarity to Ideal Solution (Fuzzy AHP-TOPSIS) method for evaluating various information security factors of a web application in order to provide effective and useful results for the developers and researchers. Furthermore, every calculation needs a validation and scientific proof in our case the study assesses the evaluated result on software of hospital from Varanasi, India. The results and ideology of this study will definitely help the practitioners in developing secure and effective information security within a web application. Moreover, the empirical analysis conducted in our research has attempted to etch a systematic path for the developers who can focus on the most prioritized factors for assured and concrete information security within a web application.