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Introduction:There is a strong demand for high quality, cost effective clinical education experiences that facilitate the students' learning in the clinical setting. Clinical teaching is a challenging task and the instructors can use strategies to change the quality of clinical instruction. This study aimed to determine the factors affecting the students' clinical skills.Material and Methods:This is a cross-sectional study on nursing students of Jahrom University of Medical Sciences who were selected through simple sampling. Data were collected through a valid and reliable questionnaire on effective strategies of clinical skills including five domains of environmental, psychosocial, students, teaching and-learning strategies, and psychosocial classified based on5 point Likret style. The highest percentage in different domains was calculated based on their importance.Results:According to the results, the mean scores of environmental, psychosocial and teacher factors were higher than teaching-and learning strategies and student factors. There was a significant relationship between environmental factors and the students' clinical skills. (p=0.05)Conclusion:We recommend that effective factors in clinical skills should be considered in curriculum planning to enhance and facilitate the students' learning skills in the clinical wards.