Generation of human induced pluripotent stem cell lines from human dermal fibroblasts using a non-integration system

oleh: Kyung-Ok Uhm, So-Jung Kim, Eun Hee Jo, Gue Youn Go, Hye Young Choi, Young Sam Im, Hye-Yeong Ha, Jung-Hyun Kim, Soo Kyung Koo

Format: Article
Diterbitkan: Elsevier 2017-05-01

Deskripsi

We generated human induced pluripotent stem cells (hiPSCs) from dermal fibroblasts using a Sendai virus (SeV)-based gene delivery method. The generated hiPSC line, KSCBi002-A, has a normal karyotype (46,XY). The pluripotency and differentiation capacity were characterized by comparison with those of a human embryonic stem cell line. This cell line is registered and available from the National Stem Cell Bank, Korea National Institute of Health.