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Abstract Leptoquarks enter in several extensions of the Standard Model as possible solutions to a number of observed anomalies. We work within the soft-collinear effective theory framework to present a detailed analysis of the decay rates of the three leptoquarks that appear the most in literature, the scalars S 1 and S 3 and the vector U 1 μ $$ {U}_1^{\mu } $$ . Using renormalization-group methods we resum the large logarithms arising from the evolution of the Wilson coefficients between the New Physics scale and the electroweak scale. We also derive the tree-level matching relations for the Wilson coefficients in the effective theory for some specific leptoquark models.