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In this research paper, human blood sensor based on dual core symmetric photonic crystal fiber (DC-S-PCF) is proposed. It is possible by infiltrating blood samples in the provided elliptical hole of the structure. As this structure exerts the different polarization and based on the coupling principle, the sensitivity of the design is achieved. As a result, it gives 13.5 nm/g/dL for the X-polarized mode and 5.96 nm/g/dL for the Y-polarized mode at 5 cm fiber length of the proposed sensor. Keywords: Dual core PCF, Polarization, Coupling properties, FEM