CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses

oleh: Phillip M. Brailey, Lauren Evans, Juan Carlos López-Rodríguez, Anthony Sinadinos, Victoria Tyrrel, Gavin Kelly, Valerie O’Donnell, Peter Ghazal, Susan John, Patricia Barral

Format: Article
Diterbitkan: Nature Portfolio 2022-11-01

Deskripsi

Modulation of metabolic pathways is linked to regulation of immune cells including macrophages. Here the authors identify a role for CD1d in the metabolic rewiring of macrophages, which alters responsiveness to innate stimuli.