TGFβ signaling curbs cell fusion and muscle regeneration
oleh: Francesco Girardi, Anissa Taleb, Majid Ebrahimi, Asiman Datye, Dilani G. Gamage, Cécile Peccate, Lorenzo Giordani, Douglas P. Millay, Penney M. Gilbert, Bruno Cadot, Fabien Le Grand
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-02-01 |
Deskripsi
The fusion of muscle progenitor cells to form syncytial myofibers is required for skeletal muscle development and regeneration. Here, the authors describe a novel and specific molecular regulation of muscle cell fusion driven by transforming growth factor beta (TGFβ) signaling.