Opposite monosynaptic scaling of BLP–vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory
oleh: Ying Yang, Zhi-Hao Wang, Sen Jin, Di Gao, Nan Liu, Shan-Ping Chen, Sinan Zhang, Qing Liu, Enjie Liu, Xin Wang, Xiao Liang, Pengfei Wei, Xiaoguang Li, Yin Li, Chenyu Yue, Hong-lian Li, Ya-Li Wang, Qun Wang, Dan Ke, Qingguo Xie, Fuqiang Xu, Liping Wang, Jian-Zhi Wang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-07-01 |
Deskripsi
How emotions affect memory is an open question. Here the authors establish learnt hopeful and learnt helpless mouse models, and find that posterior basolateral amygdala to ventral hippocampal CA1 monosynaptic glutamatergic inputs link emotions to spatial memory performance.