A CLUSTER OF SARS‐COV‐2 DELTA VARIANT OF CONCERN ADDITIONALLY HARBORING F490S, NORTHERN LOMBARDY, ITALY

oleh: Federica Novazzi, Andreina Baj, Renee Pasciuta, Angelo Genoni, Francesca Drago Ferrante, Rosalia Tripiciano, Giuseppe Catanoso, Daniele Focosi, Fabrizio Maggi

Format: Article
Diterbitkan: Elsevier 2022-03-01

Deskripsi

The Delta variant of concern (VOC) of SARS-CoV-2 has become dominant worldwide. In this article, we report a cluster caused by B.1.617.2 harboring the additional mutation of concern (MOC) F490S. We observed that 5 fully vaccinated subjects aged between 47 and 84 years were infected with this variant. The immune escape mutation F490S, first identified in the Lambda VOI, appears to impair vaccine efficacy and is rapidly increasing in prevalence worldwide.