Cell specific peripheral immune responses predict survival in critical COVID-19 patients

oleh: Junedh M. Amrute, Alexandra M. Perry, Gautam Anand, Carlos Cruchaga, Karl G. Hock, Christopher W. Farnsworth, Gwendalyn J. Randolph, Kory J. Lavine, Ashley L. Steed

Format: Article
Diterbitkan: Nature Portfolio 2022-02-01

Deskripsi

Infection with SARS-CoV-2 results in activation of multiple immune cell types in situ but also in the peripheral blood compartment. Here the authors apply single cell sequencing and machine learning to characterise the response and link this to confer prognostic indicators in critically ill COVID-19 patients.