A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family
oleh: Thomas Hermanns, Christian Pichlo, Ulrich Baumann, Kay Hofmann
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-01-01 |
Deskripsi
ZUFSP-type enzymes cleave ubiquitin chains in a linkage-specific fashion, but members from different organisms have different specificities. Using an inter-kingdom comparison of activities and structures, the authors identify the domains responsible for this discrepancy.