An Auto-Processing Algorithm for Liver Fat Quantification

oleh: ZHANG Miao, ZHAI Guo-qiang, LI Gai-ying, WANG Yi, FAN Ming-xia, LI Jian-qi

Format: Article
Diterbitkan: Science Press 2018-12-01

Deskripsi

Magnetic resonance spectroscopy (MRS) is useful for rapid and robust liver fat quantification. MR spectra of liver can be acquired in a single breath-hold with the high-speed multi-echo stimulated echo acquisition mode, from which T2-corrected liver proton density fat fraction (PDFF) can be derived. However, the widespread application of this method is hampered by the cumbersome post-processing procedures for the spectroscopy data. In this work, an automated algorithm for liver fat quantification from multi-echo spectroscopy data was developed. The feasibility and accuracy of the algorithm were evaluated with fat-water phantoms experiments and human liver experiments. The results demonstrated excellent correlation and agreement between the PDFF measurements with the proposed algorithm and those obtained with the jMRUI software.