CDC20B is required for deuterosome-mediated centriole production in multiciliated cells
oleh: Diego R. Revinski, Laure-Emmanuelle Zaragosi, Camille Boutin, Sandra Ruiz-Garcia, Marie Deprez, Virginie Thomé, Olivier Rosnet, Anne-Sophie Gay, Olivier Mercey, Agnès Paquet, Nicolas Pons, Gilles Ponzio, Brice Marcet, Laurent Kodjabachian, Pascal Barbry
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-11-01 |
Deskripsi
In vertebrate multiciliated cells, most centrioles are synthesized and released by poorly characterized structures called deuterosomes. Here, the authors report that the previously-uncharacterized Cdc20b in mouse and Xenopus associates with deuterosomes and contributes to centriole release.