SARS-CoV-2 spike opening dynamics and energetics reveal the individual roles of glycans and their collective impact
oleh: Yui Tik Pang, Atanu Acharya, Diane L. Lynch, Anna Pavlova, James C. Gumbart
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-11-01 |
Deskripsi
Molecular dynamics simulations and enhanced sampling methods reveal the role of glycans and the energetics of glycan-mediated conformational switches in the receptor binding domains of the SARS-CoV-2 trimeric spike glycoprotein.