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The study was conducted in six calves presented with septic arthritis belonging to different age, breed and sex. Among the six calves, three were affected with chronic stage of disease with joint contracture and non-weight bearing on the affected limb. Clinical signs of arthritis were noticed in all the cases. Radiography and goniometry provided information regarding response to treatment protocol adapted. Haematology and serum biochemistry were found to have limited diagnostic value. Treatment protocol formulated which contains, three stage lavaging, application of splint and empirical antibiotic therapy showed satisfactory results. The progression of the evaluation of joint disorder, efficacy of the diagnostic modalities and standardisation of treatment protocol was attempted in this study