Hypoxia-Inducible Factor 1α (HIF1α) Suppresses Virus Replication in Human Cytomegalovirus Infection by Limiting Kynurenine Synthesis
oleh: Lisa M. Wise, Yuecheng Xi, John G. Purdy
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-04-01 |
Deskripsi
Viruses, including human cytomegalovirus (HCMV), reprogram cellular metabolism using host metabolic regulators to support virus replication. Alternatively, in response to infection, the host can use metabolism to limit virus replication.