Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia

oleh: Carmen Gasca-Salas, Beatriz Fernández-Rodríguez, José A. Pineda-Pardo, Rafael Rodríguez-Rojas, Ignacio Obeso, Frida Hernández-Fernández, Marta del Álamo, David Mata, Pasqualina Guida, Carlos Ordás-Bandera, J. Ignacio Montero-Roblas, Raúl Martínez-Fernández, Guglielmo Foffani, Itay Rachmilevitch, José A. Obeso

Format: Article
Diterbitkan: Nature Portfolio 2021-02-01

Deskripsi

Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with dementia.