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Mandible, the lower jaw, creates peripheral boundaries of floor of the oral cavity, and it is the most common site for intraoral tumors which often require the resection of their large portions. Loss of continuity of the mandible leads to deviation of the residual segment toward the surgical site and alteration in muscle function. This results in facial asymmetry and malocclusion. Numerous prosthetic methods are employed to minimize deviation and improve masticatory efficiency, which include implant-supported prosthesis and palatal-based guidance restorations. This case report describes the rehabilitation of a hemimandibulectomy patient using twinned teeth (two rows of teeth) arrangement.