Plug-and-play metabolic transducers expand the chemical detection space of cell-free biosensors

oleh: Peter L. Voyvodic, Amir Pandi, Mathilde Koch, Ismael Conejero, Emmanuel Valjent, Philippe Courtet, Eric Renard, Jean-Loup Faulon, Jerome Bonnet

Format: Article
Diterbitkan: Nature Portfolio 2019-04-01

Deskripsi

The range of chemicals detectable by cell-free systems is still limited. Here the authors combine metabolic cascades with transcription factor networks to detect small molecules in complex environments.