Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity

oleh: Liya Hu, Wilhelm Salmen, Rong Chen, Yi Zhou, Frederick Neill, James E. Crowe, Robert L. Atmar, Mary K. Estes, B. V. Venkataram Prasad

Format: Article
Diterbitkan: Nature Portfolio 2022-03-01

Deskripsi

GII.4 variants of human noroviruses cause pandemic viral gastroenteritis. The atomic structure of GII.4 virus-like particles reveal novel insights into capsid stability, dynamics and antigenic presentation potentially useful for ongoing vaccine development.