Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity

oleh: Arun Vaidyanath, Mohsina Khan, Anjali Shiras

Format: Article
Diterbitkan: Elsevier 2020-05-01

Deskripsi

Two iPSC clones, NCCSi008-A and NCCSi008-B, were generated from a healthy male individual of Indian origin by reprogramming his CD4+ T cells with an integration free Sendai viral vector. The established iPSC clones showed high alkaline phosphatase (ALP) activity, expression of pluripotency markers, a normal male karyotype consistent with the donor gender (46, XY) and has potential for multi-lineage differentiation. These iPSC lines of Indian origin would serve as valuable resources for disease modeling, drug development and screening.