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Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity
oleh: Arun Vaidyanath, Mohsina Khan, Anjali Shiras
Format: | Article |
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Diterbitkan: | Elsevier 2020-05-01 |
Deskripsi
Two iPSC clones, NCCSi008-A and NCCSi008-B, were generated from a healthy male individual of Indian origin by reprogramming his CD4+ T cells with an integration free Sendai viral vector. The established iPSC clones showed high alkaline phosphatase (ALP) activity, expression of pluripotency markers, a normal male karyotype consistent with the donor gender (46, XY) and has potential for multi-lineage differentiation. These iPSC lines of Indian origin would serve as valuable resources for disease modeling, drug development and screening.