Are We Eating Our Way to Prostate Cancer—A Hypothesis Based on the Evolution, Bioaccumulation, and Interspecific Transfer of miR-150

oleh: Venkatesh Vaidyanathan, Vetrivhel Krishnamoorthy, Nishi Karunasinghe, Anower Jabed, Radha Pallati, Chi Hsiu-Juei Kao, Alice Wang, Gareth Marlow, Lynnette R. Ferguson

Format: Article
Diterbitkan: MDPI AG 2016-04-01

Deskripsi

MicroRNAs (miRNAs) are well established epigenetic modifiers. There is a lot of work being done to identify the evolutionary transfer of miRNAs both at intra- and interspecific levels. In this hypothesis-driven review, we have suggested a possible reason as to why miR-150 can be a promising diagnostic biomarker for prostate cancer using theories of evolution, bio-accumulation, and interspecific transfer of miRNAs.