Copper(I)-catalysed site-selective C(sp 3)–H bond chlorination of ketones, (E)-enones and alkylbenzenes by dichloramine-T
oleh: Jianwen Jin, Yichao Zhao, Sara Helen Kyne, Kaveh Farshadfar, Alireza Ariafard, Philip Wai Hong Chan
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-07-01 |
Deskripsi
Organochlorides are widespread in natural products, therefore the methods for site-selective chlorination at specific C–H bonds are of great interest. Here, the authors report a copper(I)-catalysed synthetic method for the efficient site-selective C(sp 3)–H bond chlorination of ketones, (E)-enones and alkylbenzenes by dichloramine-T at room temperature.