Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice

oleh: Zhi Zhang, Fernando M. C. V. Reis, Yanlin He, Jae W. Park, Johnathon R. DiVittorio, Nilla Sivakumar, J. Edward van Veen, Sandra Maesta-Pereira, Michael Shum, India Nichols, Megan G. Massa, Shawn Anderson, Ketema Paul, Marc Liesa, Olujimi A. Ajijola, Yong Xu, Avishek Adhikari, Stephanie M. Correa

Format: Article
Diterbitkan: Nature Portfolio 2020-12-01

Deskripsi

Torpor is a state of reduced metabolism and body temperature that conserves energy when food is scarce. Here the authors show that estrogen-sensitive neurons in the hypothalamus regulate torpor in mice, maintaining torpor in both sexes but initiating torpor and regulating core temperature differentially across sex.