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Background: This study aimed to investigate the relationship between Pender's Health Promotion Model constructs and applying nutritional supplements in patients with hypertension in rural areas of Isfahan Township, Iran. Methods: In a cross-sectional study, 233 patients with high blood pressure were selected from rural health centers in Isfahan Township. Patient’s dietary intake was assessed by a 3-day dietary questionnaire, and cognitive factors and a commitment to nutritional approach with Pender Health Promotion Model. The relationship between dietary intake and nutritional approach was studied as well. Findings: There was an inverse and significant relationship of 0.316 between sodium intake and knowledge (P < 0.001). Moreover, there was a significant negative correlation of 0.121 between the benefit score and the sodium intake (P = 0.002), but no relationship between other criteria (perceived self-efficacy, behavioral sensation, status affecting, and social support) and sodium intake. Conclusion: The findings of this study showed that there was a significant relationship between Pender Health Promotion Model and nutritional approaches for controlling blood pressure. Therefore, it is recommended to use Pender Health Promotion Components in health units associated with hypertension.