Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Application of Nanodiamonds in Biomolecular Mass Spectrometry
oleh: Ping Cheng, Xianglei Kong
Format: | Article |
---|---|
Diterbitkan: | MDPI AG 2010-03-01 |
Deskripsi
The combination of nanodiamond (ND) with biomolecular mass spectrometry (MS) makes rapid, sensitive detection of biopolymers from complex biosamples feasible. Due to its chemical inertness, optical transparency and biocompatibility, the advantage of NDs in MS study is unique. Furthermore, functionalization on the surfaces of NDs expands their application in the fields of proteomics and genomics for specific requirements greatly. This review presents methods of MS analysis based on solid phase extraction and elution on NDs and different application examples including peptide, protein, DNA, glycan and others. Owing to the quick development of nanotechnology, surface chemistry, new MS methods and the intense interest in proteomics and genomics, a huge increase of their applications in biomolecular MS analysis in the near future can be predicted.