Decoupling epithelial-mesenchymal transitions from stromal profiles by integrative expression analysis
oleh: Michael Tyler, Itay Tirosh
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-05-01 |
Deskripsi
Epithelial cancer cells can transition into a mesenchymal phenotype to enable invasion and metastasis. Here, the authors use previously published single-cell and bulk RNA sequencing datasets to decouple the mesenchymal expression profiles of cancer and stromal cells.