CryoEM structure and assembly mechanism of a bacterial virus genome gatekeeper

oleh: Igor Orlov, Stéphane Roche, Sandrine Brasilès, Natalya Lukoyanova, Marie-Christine Vaney, Paulo Tavares, Elena V. Orlova

Format: Article
Diterbitkan: Nature Portfolio 2022-11-01

Deskripsi

Numerous viruses use a portal system for dsDNA entry and exit from their capsid. Here the authors report the atomic structure of phage SPP1 portal DNA gatekeeper and its mechanism of assembly. They also identify evolution breakpoints between different tailed bacteriophages morphotypes and herpesviruses.