Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes
oleh: Syuan-Ming Guo, Remi Veneziano, Simon Gordonov, Li Li, Eric Danielson, Karen Perez de Arce, Demian Park, Anthony B. Kulesa, Eike-Christian Wamhoff, Paul C. Blainey, Edward S. Boyden, Jeffrey R. Cottrell, Mark Bathe
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-09-01 |
Deskripsi
Multiplexed imaging of synaptic proteins can provide useful information on the heterogeneity of synaptic architecture and plasticity. Here the authors use high affinity locked nucleic acid probes and low affinity DNA imaging probes to achieve multiplexed confocal and super-resolution imaging of synaptic and cytoskeletal proteins.