Neutrophil azurophilic granule glycoproteins are distinctively decorated by atypical pauci- and phosphomannose glycans

oleh: Karli R. Reiding, Yu-Hsien Lin, Floris P. J. van Alphen, Alexander B. Meijer, Albert J. R. Heck

Format: Article
Diterbitkan: Nature Portfolio 2021-08-01

Deskripsi

Reiding et al. performed conventional proteomics as well as glycoproteomics on protein extracts from lysates of pooled neutrophils obtained from ten healthy donors. They analyse and compare the glycan occupancy on membrane and secreted glycoproteins, which is helpful to reveal the relationship between neutrophil glycoproteins and their function.