Selective copper(II) acetate and potassium iodide catalyzed oxidation of aminals to dihydroquinazoline and quinazolinone alkaloids
oleh: Matthew T. Richers, Chenfei Zhao, Daniel Seidel
| Format: | Article |
|---|---|
| Diterbitkan: | Beilstein-Institut 2013-06-01 |
Deskripsi
Copper(II) acetate/acetic acid/O2 and potassium iodide/tert-butylhydroperoxide systems are shown to affect the selective oxidation of ring-fused aminals to dihydroquinazolines and quinazolinones, respectively. These methods enable the facile preparation of a number of quinazoline alkaloid natural products and their analogues.