Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides

oleh: Ibraheem Alshareedah, Mahdi Muhammad Moosa, Matthew Pham, Davit A. Potoyan, Priya R. Banerjee

Format: Article
Diterbitkan: Nature Portfolio 2021-11-01

Deskripsi

Here the authors show that disordered polypeptide-RNA condensates exhibit rheological properties similar to that of a viscoelastic Maxwell fluid, and use simple polypeptide design rules to create microcondensates with tunable viscoelasticity.