Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation
oleh: Ravi Kiran Koripella, Manjuli R. Sharma, Kalpana Bhargava, Partha P. Datta, Prem S. Kaushal, Pooja Keshavan, Linda L. Spremulli, Nilesh K. Banavali, Rajendra K. Agrawal
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-07-01 |
Deskripsi
Translation within mitochondria is carried out by specialized mitoribosomes and translational factors. Here the authors describe cryo-EM structures of the human mitochondrial translation elongation factor G1 in complex with human mitoribosomes, revealing distinct mechanism that include conformational changes at the polypeptide exit tunnel.