A modular vaccine platform enabled by decoration of bacterial outer membrane vesicles with biotinylated antigens
oleh: Kevin B. Weyant, Ayomide Oloyede, Sukumar Pal, Julie Liao, Mariela Rivera-De Jesus, Thapakorn Jaroentomeechai, Tyler D. Moeller, Steven Hoang-Phou, Sean F. Gilmore, Riya Singh, Daniel C. Pan, David Putnam, Christopher Locher, Luis M. de la Maza, Matthew A. Coleman, Matthew P. DeLisa
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
Antigen display on outer membrane vesicles (OMVs) can be difficult to control and highly variable. Here, the authors describe a universal approach called AvidVax for linking biotinylated antigens to the exterior of OMVs and enabling rapid vaccine assembly.