Mammalian N1-adenosine PARylation is a reversible DNA modification

oleh: Michael U. Musheev, Lars Schomacher, Amitava Basu, Dandan Han, Laura Krebs, Carola Scholz, Christof Niehrs

Format: Article
Diterbitkan: Nature Portfolio 2022-10-01

Deskripsi

Poly-ADP-ribosylation (PARylation) is a well-known posttranslational modification of proteins. Here the authors show that beyond proteins also mammalian single-stranded DNA is PARylated in vitro and in vivo.