Thermostability and in vivo performance of AAV9 in a film matrix
oleh: Trang Nguyen Kieu Doan, Matthew D. Le, Irnela Bajrovic, Lorne Celentano, Charles Krause, Haley Grooms Balyan, Abbie Svancarek, Angela Mote, Anna Tretiakova, R. Jude Samulski, Maria A. Croyle
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-11-01 |
Deskripsi
Doan et al. characterize and assess the stability of film matrix embedded Adeno-Associated Virus 9 (AAV9) vectors during storage and transport at ambient temperatures. High and low viscosity formulations of AAV9 stored at 25 °C maintain titer for 6 months.