Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration

oleh: Yong Shao, Xiao-Bo Wang, Jin-Jin Zhang, Ming-Li Li, Shou-Song Wu, Xi-Yao Ma, Xue Wang, Hui-Fang Zhao, Yuan Li, Helen He Zhu, David M. Irwin, De-Peng Wang, Guo-Jie Zhang, Jue Ruan, Dong-Dong Wu

Format: Article
Diterbitkan: Nature Portfolio 2020-05-01

Deskripsi

The mechanisms regulating regeneration of the earthworm are unclear. Here, the authors use genomic and transcriptomic analysis of the earthworm Eisenia andrei together with Hi-C analysis to identify genes involved and show activation of LINE2 transposable elements on regeneration.