Methyl 11-hydroxy-9-[1-(4-methoxyphenyl)-4-oxo-3-phenylazetidin-2-yl]-18-oxo-10-oxa-2-azapentacyclo[9.7.0.01,8.02,6.012,17]octadeca-12(17),13,15-triene-8-carboxylate
oleh: Devadasan Velmurugan, Raghavachary Raghunathan, Raju Rajesh, Thothadri Srinivasan, Sivasubramanian Suhitha
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2013-03-01 |
Deskripsi
In the title compound, C34H32N2O7, the furan ring adopts a twist conformation and both the pyrrolidine rings adopt envelope conformations with O and C as flap atoms. The β-lactam ring makes a dihedral angles of 80.20 (10)° with the furan ring, of 75.55 (10)° with the pyrrolidine ring, of 12.26 (10)° with the methoxyphenyl ring and of 73.77 (13)° with the phenyl ring. The O atom attached to the β-lactam ring deviates by 0.0385 (13) Å from the ring plane. The molecular conformation is stabilized by intramolecular O—H...N and C—H...O hydrogen bonds. The packing of the crystal is stabilized by intermolecular C—H...O hydrogen bonds, which form a chain running along the b axis.